NVDA vs. LLY Investment Analysis: Portfolio Allocation & Growth Trajectory
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Based on my comprehensive analysis of both NVIDIA (NVDA) and Eli Lilly (LLY), here are the key factors investors should consider when deciding whether to maintain long-term positions in NVIDIA versus rotating into pharmaceutical stocks:
- NVDA’s Massive Size: At $4.29 trillion market cap, NVIDIA represents 15%+ of many tech-heavy portfolios, creating significant concentration risk [0]
- Sector Diversification: Technology currently underperforms (-1.40%) while Healthcare leads (+0.73%) [0], suggesting sector rotation benefits
- Market Cap Distribution: LLY at $954 billion provides large-cap exposure without extreme concentration in a single position
- NVDA’s Recent Performance: -7.39% over the past month with sideways technical indicators, suggesting momentum shift [0]
- LLY’s Momentum: +38.97% over 3 months, benefiting from healthcare sector strength [0]

- Explosive Historical Growth: 962.88% over 3 years, driven by AI revolution [0]
- Current Growth Deceleration: 90-day performance of -2.90% indicates recent stagnation [0]
- Future Catalysts: Recent acquisition of SchedMD to enhance AI ecosystem [1], continued AI infrastructure build-out
- Revenue Concentration: 88.3% from Data Center segment, creating single-product dependency risk [0]
- Consistent Outperformance: 195.30% over 3 years, +62.25% over past 90 days [0]
- Pharmaceutical Leadership: Dominant position in GLP-1 weight loss drugs with orforglipron oral GLP-1 expected launch in H2 2026 [2]
- Diversified Pipeline: Expanding beyond obesity into multiple therapeutic areas
- Market Underappreciation: Bank of America believes obesity drug dominance remains underpriced [2]
- NVDA: High beta of 2.28 (128% more volatile than market), daily volatility of 2.13% [0]
- LLY: Low beta of 0.37 (63% less volatile than market), daily volatility of 1.96% [0]
- NVDA: P/E of 43.19x, DCF analysis suggests significant overvaluation with fair values between $68-113 vs current $176 [0]
- LLY: P/E of 51.77x appears high but DCF shows fair value range of $547-1,654 with current $1,063 within reasonable range [0]
- NVDA: Conservative financial attitude, strong margins (58.84% operating), low debt risk [0]
- LLY: Conservative accounting, strong margins (43.86% operating), moderate debt risk [0]
Consider reducing NVDA exposure and rotating into LLY for better risk-adjusted returns. LLY provides healthcare sector diversification with lower volatility and strong growth momentum.
Maintain core NVDA position but consider partial profit-taking. NVIDIA’s AI infrastructure thesis remains intact long-term, but current valuation suggests near-term consolidation risk.
- Core Technology: 60-70% allocation to NVDA for long-term AI exposure
- Healthcare Growth: 30-40% allocation to LLY for diversification and defensive positioning
- Market Timing: Consider rotating a portion of NVDA holdings to LLY during technology sector weakness
- Valuation Gap: NVDA appears 49-61% overvalued by DCF metrics vs LLY’s fair valuation [0]
- Momentum Shift: Technology sector underperforming while healthcare leads [0]
- Risk Management: LLY offers superior risk-adjusted returns with lower volatility
- Growth Catalysts: Both have strong pipelines, but LLY’s nearer-term catalysts (Orforglipron 2026) provide more predictable timing
- Portfolio Balance: Rotation into LLY reduces concentration risk while maintaining exposure to disruptive innovation
The recent market dynamics favor a strategic rotation approach, though maintaining some NVIDIA exposure preserves participation in the ongoing AI revolution while reducing overall portfolio risk through healthcare diversification.
[0] Ginlix API Data
[1] NVIDIA (NVDA) Acquires SchedMD to Enhance AI Ecosystem - GuruFocus (https://www.gurufocus.com/news/4070801/nvidia-nvda-acquires-schedmd-to-enhance-ai-ecosystem)
[2] Eli Lilly’s Obesity Drug Dominance Still Underpriced By Market, Bank of America Says - Benzinga (https://www.benzinga.com/analyst-stock-ratings/analyst-color/25/12/49399288/eli-lilly-obesity-growth-orfoglipron-glp-1-pill-weight-loss-bank-america)
Insights are generated using AI models and historical data for informational purposes only. They do not constitute investment advice or recommendations. Past performance is not indicative of future results.
