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WuXi Biologics' ADC Drug CMO Business Backlog Reaches USD 1.33 Billion

#biopharma #adc #cmo_cdmo #order_book #acquisition #capacity_expansion #hong_kong_stocks
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January 20, 2026

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Based on the latest information I have obtained, details regarding the backlog of WuXi Biologics (HK02269) ADC Drug CMO Business are as follows:

Backlog of WuXi Biologics’ ADC Drug CMO Business
Core Data

As of the end of 2025, WuXi XDC (a subsidiary of WuXi Biologics focused on ADC/XDC business) had a backlog of USD 1.33 billion (equivalent to approximately RMB 9.45 billion), representing a year-on-year increase of 57.9%
[1][2].

Business Details

1. Overview of WuXi XDC (02268.HK)

  • WuXi XDC is an ADC/XDC bioconjugate drug CRDMO platform jointly established by WuXi Biologics (02269.HK) and WuXi AppTec via its subsidiary WuXi STA
  • Based on revenue, it is
    the world’s second-largest CRDMO for ADC and other bioconjugate drugs
    , with its market share increasing from 9.9% in 2022 to 22-24% in 2025[1][3]

2. Business Scale

  • Over
    630 collaborative clients worldwide
  • Total number of iCMC projects:
    252
  • Including
    18 PPQ (Process Performance Qualification) projects
    and
    1 commercial-scale project
  • Total number of integrated projects reaches
    225
    [1][2]

3. Project Structure (As of the end of 2025)

  • Phase III clinical projects:
    23
  • Commercial production projects:
    1
  • ADC projects account for
    33%
    of WuXi Biologics’ total projects (945 in total), representing a year-on-year increase of
    30%
    [4]
Performance (First Half of 2025)
  • Revenue:
    RMB 2.7 billion
    , with a year-on-year growth of
    62.2%
  • Net profit attributable to parent company:
    RMB 746 million
    , with a year-on-year growth of
    52.74%
  • Gross profit margin: Over
    70%
    [1][2]
Strategic Layout

WuXi XDC recently announced the acquisition of Shanghai Topscience Pharma for

HKD 3.091 billion
, aiming to quickly acquire mature ADC commercial production capacity and strengthen its leading position in the global ADC CDMO space[3].


References

[1] PharnexCloud - WuXi XDC Acquires Shanghai Topscience Pharma with 99% Premium! Capacity Expansion + Ecological Positioning (https://www.pharnexcloud.com/zixun/sx_267871)

[2] Sina Finance - WuXi XDC, Leading ADC Outsourcing Provider, Acquires Shanghai Topscience Pharma with Over 100% Premium to “Race Against Time” (https://finance.sina.com.cn/jjxw/2026-01-16/doc-inhhnzaw0684693.shtml)

[3] Pharmcube ByDrug - HKD 3.091 Billion: China’s Top ADC CDMO Makes Another Acquisition (https://bydrug.pharmcube.com/news/detail/4b6c8a9370e413a26df1896bd5a0947c)

[4] Gelonghui - WuXi Biologics Unleashes Stunning M-Segment Volume Growth; WuXi AppTec Earned Over RMB 13 Billion in Net Profit Last Year! (https://news.qq.com/rain/a/20260113A01IMM00)

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Insights are generated using AI models and historical data for informational purposes only. They do not constitute investment advice or recommendations. Past performance is not indicative of future results.